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Licensable Assets - Overview

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Pitch Decks

NB-001: Dual-Target PIM/CDK Inhibitor for Hematologic Malignancies

NB-001: Dual-Target PIM/CDK Inhibitor for Hematologic Malignancies

NB-001: Dual-Target PIM/CDK Inhibitor for Hematologic Malignancies

 A breakthrough in targeted therapeutics for acute myeloid leukemia and non-Hodgkin lymphoma. This innovative compound simultaneously inhibits PIM1/2/3 and CDK2/4/6 kinases, disrupting critical downstream signaling pathways that drive tumor cell differentiation and proliferation. 

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NB-005: Best-in-Class DLL3-Targeted ADC

NB-001: Dual-Target PIM/CDK Inhibitor for Hematologic Malignancies

NB-001: Dual-Target PIM/CDK Inhibitor for Hematologic Malignancies

 A breakthrough antibody-drug conjugate (ADC) targeting DLL3 for small cell lung cancer (SCLC) and other neuroendocrine tumors 

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NB-007: Next-Generation Dual-Targeting FLT3/CSF1R Inhibitor

NB-001: Dual-Target PIM/CDK Inhibitor for Hematologic Malignancies

NB-007: Next-Generation Dual-Targeting FLT3/CSF1R Inhibitor

 A breakthrough approach in hematologic oncology, simultaneously targeting the FLT3 and CSF1R pathways to address both tumor cells and the immunosuppressive tumor microenvironment. This dual mechanism offers a differentiated therapeutic strategy for acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). 

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NB-008 – Best-in-Class Oral PCSK9 Inhibitor

NB-009 First-in-Class Candidate for RAS Tumors

NB-007: Next-Generation Dual-Targeting FLT3/CSF1R Inhibitor

 Transforming cardiovascular and oncology treatment with the first oral small molecule PCSK9 inhibitor, delivering unmatched patient convenience and expanded access to life-saving therapy. 

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NB-009 First-in-Class Candidate for RAS Tumors

NB-009 First-in-Class Candidate for RAS Tumors

NB-009 First-in-Class Candidate for RAS Tumors

 Polysaccharide Drug Conjugate

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NB-010: Anti-PD-L1 ADC

NB-009 First-in-Class Candidate for RAS Tumors

NB-009 First-in-Class Candidate for RAS Tumors

 First-in-class, IND-ready, anti-PD-L1 ADC with targeted cytotoxic delivery and immune checkpoint inhibition 

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NB-011: Tumor MicroEnvironment Activated (TMEA) - Legubicin

NB-011: Tumor MicroEnvironment Activated (TMEA) - Legubicin

NB-011: Tumor MicroEnvironment Activated (TMEA) - Legubicin

Innovative Platform and Pipeline: Transforming cancer treatment through tumor-specific activation technology. 

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NB-012: AKT-1 ASO for Hepatocellular Carcinoma

NB-011: Tumor MicroEnvironment Activated (TMEA) - Legubicin

NB-011: Tumor MicroEnvironment Activated (TMEA) - Legubicin

 Clinical-stage antisense oligonucleotide (ASO) therapeutic targeting AKT-1, with potential across a range of cancer types.  

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NB-013: TLR9 Agonist CpG-ODN LNP for Solid Tumors

NB-011: Tumor MicroEnvironment Activated (TMEA) - Legubicin

NB-013: TLR9 Agonist CpG-ODN LNP for Solid Tumors

 Proprietary CpG-ODN LNP formulation functioning as a TLR9 agonist designed to reinvigorate anti-tumor immunity. 

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